History: Lemons
Lemons have been used since ancient times for their rejuvenative qualities.

Lemons were originally developed as a cross between the lime and the citron and are thought to have originated in China and in India, having been cultivated in these regions for about 2,500 years.

Alexander the Great took them to Greece, and throughout the Classical period they were an expensive luxury food. With the fall of the Roman Empire, lemons disappeared completely from Europe, until the Crusaders discovered them in Palestine in the 13th Century.

Their first introduction to Europe was by Arabs who brought them to Spain in the 11th century around the same time that they were introduced into Northern Africa. The Crusaders, who found the fruit growing in Palestine, are credited with bringing the lemon to other countries across Europe. From the 15th Century, lemons became the principle souring agent in European cuisine, but it wasn’t until the late 18th Century, long before the discovery of Vitamin “C”, that their medicinal qualities were recognized in the West. At this time, the British Navy was losing more men to the disease scurvy than it was losing in combat. When Admiralty started adding lemon juice to the sailors’ daily half-pint ration of rum, the mortality rate immediately declined.

Like many other fruits and vegetables, lemons were brought to the Americas by Christopher Columbus in his second voyage to the New World in 1493, and have been grown in Florida since the 16th century. Lemons, like other vitamin-C rich fruits, were highly prized by the miners and developers during the California Gold Rush in the mid-19th century, since they were used to protect against the development of scurvy. They were in such demand that people were willing to pay up to $1 per lemon, a price that would still be considered costly today and was extremely expensive back in 1849. The major producers of lemons today are the United States and Italy as well as Spain, Greece, Israel, Lebanon and Turkey.

Healthy Compounds.
Lemon contain unique flavonoid compounds that have antioxidant and anti-cancer properties. While these flavonoids have been shown to stop cell division in many cancer cell lines, they are perhaps most interesting for their antibiotic effects. In several villages in West Africa where cholera epidemics had occurred, the inclusion of lime juice during the main meal of the day was determined to have been protective against the contraction of cholera. (Cholera is a disease triggered by activity of the bacteria called Vibrio cholera). Researchers quickly began to experiment with the addition of lime juice to the sauce eaten with rice, and in this role, lime juice was also found to have a strong protective effect against cholera.

Several other fascinating research studies on the healing properties of lemons have shown that cell cycles - including the decision a cell makes about whether to divide (called mitosis) or die (apoptosis) – are altered by lime juice, as are the activities of special immune cells called monocytes.

In addition to their unique phytonutrient properties, lemons are an excellent source of one of the most important antioxidants in nature, vitamin C. Vitamin C is one of the main antioxidants found in food and the primary water-soluble antioxidant in the body. Vitamin C travels through the body neutralizing any free radicals with which it comes into contact in the aqueous environments in the body both inside and outside cells. Free radicals can interact with the healthy cells of the body, damaging them and their membranes, and also cause a lot of inflammation, or painful swelling, in the body. This is one of the reasons that vitamin C has been shown to be helpful for reducing some of the symptoms of osteoarthritis and rheumatoid arthritis.

Since free radicals can damage blood vessels and can change cholesterol to make it more likely to build up in artery walls, vitamin C can be helpful for preventing the development and progression of atherosclerosis and diabetic heart disease. Vitamin C is also vital to the function of a strong immune system. The immune system’s main goal is to protect you from illness, so a little extra vitamin C may be useful in conditions like colds, flu’s, and recurrent ear infections. Owing to the multitude of vitamin C's health benefits, it is not surprising that research has shown that consumption of vegetables and fruits high in this nutrient is associated with a reduced risk of death from all causes including heart disease, stroke and cancer.

Cancer Protection from Limonins
In animal studies and laboratory tests with human cells, compounds in citrus fruits, including lemons, called limonoids have been shown to help fight cancers of the mouth, skin, lung, breast, stomach and colon. Now, scientists from the US Agricultural Research Service have shown that our bodies can readily absorb and utilize a very long-acting limonoid called limonin that is present is citrus fruits in about the same amount as vitamin C.

In citrus fruits, limonin is present in the form of limonin glucoside, in which limonin is attached to a sugar (glucose) molecule. Our bodies easily digest this compound, cleaving off the sugar and releasing limonin.

In the ARS study, 16 volunteers were given a dose of limonin glucoside in amounts ranging from those that would be found in from 1 to 7 glasses of orange juice. Blood tests showed that limonin was present in the plasma of all except one of the subjects, with concentrations highest within 6 hours after consumption. Traces of limonin were still present in 5 of the volunteers 24 hours after consumption!
Limonin's bioavailability and persistence may help explain why citrus limonoids are potent anti-carcinogens that can continuously prevent cancerous cells from proliferating. Other natural anti-carcinogens are available for much less time; for example, the phenols in green tea and chocolate remain active in the body for just 4 to 6 hours.

Protection against Macular Degeneration
Your mother may have told you carrots would keep your eyes bright as a child, but as an adult, it looks like fruit is even more important for keeping your sight. Data reported in a study published in the June 2004 issue of the Archives of Ophthalmology indicates that eating 3 or more servings of fruit per day may lower your risk of age-related macular degeneration (ARMD), the primary cause of vision loss in older adults, by 36%, compared to persons who consume less than 1.5 servings of fruit daily.

In this study, which involved 77,562 women and 40,866 men, researchers evaluated the effect of study participants' consumption of fruits; vegetables; the antioxidant vitamins A, C, and E; and carotenoids on the development of early ARMD or neovascular ARM, a more severe form of the illness associated with vision loss. Food intake information was collected periodically for up to 18 years for women and 12 years for men. While, surprisingly, intakes of vegetables, antioxidant vitamins and carotenoids were not strongly related to incidence of either form of ARM, fruit intake was definitely protective against the severe form of this vision-destroying disease. Three servings of fruit may sound like a lot to eat each day, but lemons and limes can help you reach this goal. Dress your fruit salads with lime juice. Green salads perk up with a splash of freshly squeezed lemon juice and olive oil. Add slices of lemon or lime to your water. Top any fish dish with lemon or lime slices.

Protection against Rheumatoid Arthritis
While one July 2004 study suggests that high doses of supplemental vitamin C makes osteoarthritis, a type of degenerative arthritis that occurs with aging, worse in guinea pigs, another indicates that vitamin C-rich foods, such as lemons, provide humans with protection against inflammatory polyarthritis, a form of rheumatoid arthritis involving two or more joints.

The findings, presented in the Annals of the Rheumatic Diseases were drawn from a study of more than 20,000 subjects who kept diet diaries and were arthritis-free when the study began, and focused on 73 subjects who developed inflammatory polyarthritis and 146 similar subjects who remained arthritis-free during follow-up between 1993 and 2001. Subjects who consumed the lowest amounts of vitamin C-rich foods were more than three times more likely to develop arthritis than those who consumed the highest amounts.

How to Select and Store Lemons
One of the tricks to finding a good quality lemon is to find one that is rather thin-skinned since those with thicker peels will have less flesh and therefore be less juicy. Therefore, choose lemons that are heavy for their size and that feature peels that have a finely grained texture. They should be fully yellow in color as those that have green tinges will be more acidic due to the fact that they have not fully ripened. Signs of over mature fruit include wrinkling, soft or hard patches and dull coloring. Fresh lemons are available all year round.

Lemons will stay fresh kept at room temperature, away from exposure to sunlight, for about one week. If you will not be using them within this time period, you can store the lemons in the refrigerator crisper where they will keep for about four weeks.

Lemon juice and zest can also be stored for later use. Place freshly squeezed lemon juice in ice cube trays until frozen, subsequently storing them in plastic bags in the freezer. Dried lemon zest should be stored in a cool and dry place in an airtight glass container.